Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors
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United States of America Patent
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Feb 5, 2013
Grant Date -
Mar 3, 2011
app pub date -
May 18, 2010
filing date -
Apr 5, 2002
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Abstract
Monoclonal antibodies and hybridomas producing them that interact with osteoprotegerin ligand (OPGL) are provided. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are also provided. Methods of detecting the amount of OPGL in a sample using antibodies to OPGL are further provided.
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