Hydroxy-bisphosphonic acid derivatives as vector targeting bone tissue
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United States of America Patent
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Jan 29, 2013
Grant Date -
Dec 9, 2010
app pub date -
Jan 5, 2009
filing date -
Jan 3, 2008
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Abstract
The present invention relates to hydroxy-bisphosphonic acid derivatives corresponding to general formula (I): in which: -n and m denote, independently of one another, an integer ranging from 1 to 4, —X denotes an oxygen atom or an N—R3 group, —R1 and R3 denote, independently of one another, a linear or branched C1 to C6 alkyl group, and —R2 denotes a residue of a molecule of therapeutic or diagnostic interest, or pharmaceutically acceptable salts of said derivatives, and also the method for the preparation thereof and the therapeutic or diagnostic use thereof.
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