Ezrin assay method for the in vitro diagnosis of colorectal cancer

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United States of America Patent

PATENT NO 8361731
SERIAL NO

12452038

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Abstract

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A method for the in vitro diagnosis of colorectal cancer by determining the presence of the Ezrin tumor marker in a biological sample taken from a patient suspected of having colorectal cancer using at least one anti-Ezrin monoclonal antibody directed against an Ezrin epitope chosen from the epitopes of sequence SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3, SEQ ID No. 4+SEQ ID No. 5, SEQ ID No. 6+SEQ ID No. 7 and SEQ ID No. 8. Said method can be used for early diagnosis, screening, therapeutic follow-up and prognosis, and also for relapse diagnosis in relation to colorectal cancer.

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Patent Owner(s)

Patent OwnerAddress
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE75794 PARIS CEDEX 16
INSTITUT CURIE75248 PARIS CEDEX 05
BIOMERIEUX CHEMIN DE L'ORMEF-69280 MARCY L'ETOILE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arpin, Monique Paris, FR 7 18
Ataman-Onal, Yasmin Reyrieux, FR 1 2
Beaulieu, Corinne Rillieux la Pape, FR 9 132
Busseret, Sandrine Lyons, FR 12 24
Charrier, Jean-Philippe Tassin la Demi-Lune, FR 38 284
Choquet-Kastylevsky, Genevieve Francheville, FR 18 232
Rolland, Dominique Saint Genis les Ollieres, FR 8 96

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