Monoclonal antibodies specific for human interferon-alpha subtype alpha 8

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United States of America Patent

PATENT NO 8357782
APP PUB NO 20110091968A1
SERIAL NO

12933768

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Abstract

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The present invention has the first object to provide a monoclonal antibody specific to interferon α subtype α8 (IFNα8) and its mutant proteins, the second object to provide a hybridoma capable of producing the monoclonal antibody, the third object to provide a method for detecting the IFNα8 and its mutant proteins by the monoclonal antibody, the fourth object to provide a method for purifying the IFNα8 and its mutant proteins by the monoclonal antibody, and the fifth object to provide a therapeutic agent for treating diseases whose onsets or exacerbation are related with IFNα8. The present invention solves the above objects by providing a monoclonal antibody specific to IFNα8 and its mutant proteins, a hybridoma capable of producing the monoclonal antibody, a method for detecting the IFNα8 and its mutant proteins by immunoreaction using the monoclonal antibody, a method for purifying the IFNα8 and its mutant proteins using the monoclonal antibody, and a therapeutic agent for treating diseases whose onsets or exacerbation are related with IFNα8, which contains the monoclonal antibody as an effective ingredient.

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Patent Owner(s)

Patent OwnerAddress
KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJOOKAYAMA COUNTY JAPAN OKAYAMA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ariyasu, Harumi Okayama, JP 3 26
Ariyasu, Toshio Okayama, JP 12 26
Fukuda, Shigeharu Okayama, JP 90 956
Kayano, Tohru Okayama, JP 2 24
Ohta, Tsunetaka Okayama, JP 15 150
Ushio, Chie Okayama, JP 1 24

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