Methods for stimulating an immune response using bacterial antigen delivery system

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United States of America Patent

PATENT NO 8357373
SERIAL NO

12083188

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to the use of the type III secretion system of bacteria to stimulate immune responses against tumor antigen(s) for treating antigen-loss variant tumors. Methods are provided for stimulating and/or increasing an immune response against tumor antigens. The invention also relates to the preparation of antigen presenting cells from peripheral blood mononuclear cells using bacteria having a type III secretion system.

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Patent Owner(s)

Patent OwnerAddress
YALE UNIVERSITYTWO WHITNEY AVENUE NEW HAVEN CT 06510

International Classification(s)

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  • 2006 Application Filing Year
  • A61K Class
  • 9598 Applications Filed
  • 4848 Patents Issued To-Date
  • 50.52 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2006200720082009201020112012201320142015201620172018201920202021202220230255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Galan, Jorge E New Haven, US 6 96
Gnjatic, Sacha New York, US 13 86
Nishikawa, Hiroyoshi New York, US 12 66
Old, Lloyd J New York, US 146 3606
Ritter, Gerd New York, US 114 2436

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges93340159383591527830328862201 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +025050075010001250150017502000225025002750300032503500375040004250

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