Skin treatments containing carboxylic acid-substituted idebenone derivatives and methods of preparation and use thereof
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United States of America Patent
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Jan 15, 2013
Grant Date -
May 24, 2012
app pub date -
Jan 13, 2012
filing date -
Oct 6, 2008
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Abstract
The present invention relates to novel carboxylic acid-substituted idebenone derivatives, skin treatment compositions containing these carboxylic acid-substituted idebenone derivatives, methods of treating skin changes by topical application of these carboxylic acid-substituted idebenone derivatives, and their methods of synthesis. The carboxylic acid-substituted idebenone derivatives of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the carboxylic acid-substituted idebenone derivatives of the present invention have an antioxidant effect that is useful in treating a skin change.
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