NY-ESO-1 peptide analogs
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United States of America Patent
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Jan 15, 2013
Grant Date -
May 4, 2006
app pub date -
Jun 17, 2005
filing date -
Jun 17, 2004
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Some embodiments relate to analogs of peptides corresponding to class I MHC-restricted T cell epitopes and methods for their generation. These analogs can contain amino acid substitutions at residues that directly interact with MHC molecules, and can confer improved, modified or useful immunologic properties. Additionally classes of analogs, in which the various substitutions comprise the non-standard residues norleucine and/or norvaline, are disclosed.
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