Stable 6-methoxy-2′,3′-dideoxyguanosine, method for preparing the same and pharmaceutical composition containing the same
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United States of America Patent
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Jan 8, 2013
Grant Date -
Dec 9, 2010
app pub date -
Oct 10, 2008
filing date -
Jan 17, 2008
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Abstract
A stable 6-methoxy-2′,3′-dideoxyguanosine comprises 6-30% water content. It is prepared by absorbing water in 6-methoxy-2′,3′-dideoxyguanosine with less than 6% water content at low temperature and certain humidity, or drying 6-methoxy-2′,3′-dideoxyguanosine with more than 30% water content. The stable 6-methoxy-2′,3′-dideoxyguanosine can be used to prepare medicament composition, and be used to manufacture pharmaceutical for fighting hepatitis B virus or HIV.
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