Sonication of a medium
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United States of America Patent
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Jan 1, 2013
Grant Date -
Dec 18, 2008
app pub date -
May 5, 2006
filing date -
May 9, 2005
priority date (Note) -
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status (Latency Note)
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Abstract
Sonication of a medium for example in an immunassay is provided by applying sound waves from a transducer to a vessel in which the medium is held by a sonotrode coupled between the transducer and the vessel. The sonotrode has a recess in which the vessel is held, the recess being formed by facing surfaces of a plurality of protruding portions of the sonotrode separated by slits and arranged around the recess. The sonotrode is coupled to the vessel by dry contact with the vessel without any coupling layers therebetween. The use of such a sonotrode provides the advantages of allowing effective sonication with relatively low energy loss and with a low temperature elevation.
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