3-aryl-5,6-disubstituted pyridazines
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United States of America Patent
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Dec 25, 2012
Grant Date -
Jun 30, 2011
app pub date -
May 6, 2005
filing date -
May 8, 2004
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Expired
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Abstract
The present invention provides compounds of Formula (I) or (II) salt form or prodrug thereof, wherein variables are defined herein, that are modulators of metalloproteases such as matrix metalloproteases (MMPs) and ADAMs. The compounds or compositions described herein can be used to treat diseases associated with metalloprotease activity including, for example, arthritis, cancer, cardiovascular disorders, skin disorders, inflammation or allergic conditions.
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