Macrocyclic compounds for inhibition of tumor necrosis factor alpha
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United States of America Patent
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Dec 25, 2012
Grant Date -
Jun 17, 2010
app pub date -
Aug 20, 2009
filing date -
Aug 20, 2008
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Expired
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Abstract
Disclosed herein are macrocyclic compounds and methods for their synthesis and use. In particular, macrocyclic compounds are disclosed that modulate the activity of tumor necrosis factor alpha and/or are useful in the treatment of medical conditions, such as, rheumatoid arthritis, psoriasis, and asthma.
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