Three-branched polyethylene glycol-G-CSF conjugate
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United States of America Patent
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Dec 11, 2012
Grant Date -
Apr 29, 2010
app pub date -
Nov 22, 2006
filing date -
Nov 17, 2006
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Abstract
The present invention relates to three-branched PEG-G-CSF conjugate of general formula (1) in which the bonding ratio of three-branched polyethylene glycol (PEG) and G-CSF is 1:1 (mol/mol), wherein PEG has an average molecular weight of from 200 to 45,000 daltons; a pharmaceutical composition comprising the same, and a preparing method thereof.
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