Alkylthio pyrimidines as CRTH2 antagonists
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United States of America Patent
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Dec 4, 2012
Grant Date -
Nov 25, 2010
app pub date -
Sep 24, 2008
filing date -
Sep 25, 2007
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Abstract
Provided herein are alkylthio substituted pyrimidine compounds having CRTH2 (G-protein-coupled chemoattractant receptor, expressed on Th2 cells) antagonistic activity, useful for the treatment or prophylaxis of diseases associated with CRTH2 activity, including the treatment of allergic diseases, eosinophil-related diseases and basophil-related diseases.
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