Magnetic nanoparticle-supported glutathione as a sustainable organocatalyst

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United States of America Patent

PATENT NO 8324125
APP PUB NO 20110054180A1
SERIAL NO

12553681

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Abstract

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This invention relates to the use of nano-organocatalysts, and, more specifically, to the use of magnetic nanomaterial-supported organocatalysts. It is an object of the present invention to provide “green” catalysts and protocols. According to one embodiment of the invention, a nano-organocatalyst in the form of a magnetic nanomaterial-supported organocatalyst is provided. According to other embodiments of the invention, glutathione and cysteine are provided as organocatalysts and magnetic nanomaterial-supported glutathione and magnetic nanomaterial-supported cysteine are provided for use as nano-organocatalysts. According to another embodiment of the invention, a method of using a recyclable magnetic nanomaterial-supported organocatalyst using a totally benign aqueous protocol, without using any organic solvent in the reaction or during the workup, is provided. According to a further embodiment of the invention, a recyclable magnetic nanomaterial-supported organocatalyst for various organocatalytic reactions, including but not limited to Paal-Knorr reactions, aza-Michael addition and pyrazole synthesis, is provided.

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Patent Owner(s)

Patent OwnerAddress
UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE UNITED STATES ENVIRONMENTAL PROTECTION AGENCY1200 PENNSYLVANIA AVE N W WASHINGTON DC 20460

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Polshettiwar, Vivek Cincinnati, US 8 85
Varma, Rajender S Cincinnati, US 17 433

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