HIV vaccines based on adenoviral vectors encoding Env from multiple clades of HIV
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United States of America Patent
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Dec 4, 2012
Grant Date -
Nov 10, 2011
app pub date -
Apr 14, 2011
filing date -
Sep 15, 2003
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Abstract
The invention provides a composition comprising four adenoviral vectors, each comprising a nucleic acid sequence encoding a clade A HIV Env protein, a clade B HIV Env protein, a clade C HIV Env protein, and a clade B HIV Gag-Pol fusion protein, respectively. The invention also provides a method of inducing an immune response against HIV-1 in an animal comprising administering the composition to the animal.
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