Synthetic peptides immuno-reactive with rheumatoid arthritis auto-antibodies
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United States of America Patent
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Nov 27, 2012
Grant Date -
Mar 17, 2011
app pub date -
Dec 3, 2008
filing date -
Dec 3, 2007
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Abstract
Embodiments of the present invention relate to a three dimensional matrix of selected, synthetic peptide mimic sequences that are preferentially recognized by auto-antibodies, specifically by autoimmune antibodies, to be detected in patients afflicted with rheumatic arthritis, enabling enhanced sensitivity and specificity in detection of these antibodies in pre-symptomatic patients, in patients showing symptoms as well as patients confirmed positive for rheumatoid arthritis.
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