liver stage antigens

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United States of America Patent

PATENT NO 8318183
SERIAL NO

12722439

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Abstract

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The invention provides isolated liver stage Plasmodium polypeptides comprising an amino acid sequence selected from the group consisting of SEQ ID NOs:1-48 and immunogenic derivatives thereof. The invention also provides isolated nucleic acid molecules encoding the liver stage Plasmodium polypeptides of the invention, compositions comprising one or more liver stage Plasmodium polypeptides of the invention, methods for inducing an immune response against the liver stage Plasmodium polypeptides, and methods for treating and diagnosing liver stage malaria.

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Patent Owner(s)

Patent OwnerAddress
SEATTLE BIOMEDICAL RESEARCH INSTITUTESEATTLE WA 98109-5219

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bacik, Igor Rockville, US 5 70
Bergman, Lawrence W Landsdale, US 5 7
Duffy, Patrick Seattle, US 32 764
Heppner, Donald G Vienna, US 1 2
Kappe, Stefan H I Seattle, US 10 23
Krzych, Urszula Washington, US 2 7
Malkov, Vladislav A Seattle, US 2 7
Tarun, Alice Shoreline, US 2 2
Wendler, Jason P Lincoln, US 4 11

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