2-S-benzyl substituted pyrimidines as CRTH2 antagonists

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United States of America Patent

PATENT NO 8314116
APP PUB NO 20100240685A1
SERIAL NO

12679893

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Abstract

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Provided herein are 2-S-benzyl pyrimidine compounds having CRTH2 (G-protein-coupled chemoattractant receptor, expressed on Th2 cells) antagonistic activity, useful for the prophylaxis and treatment of diseases associated with CRTH2 activity, including the treatment of allergic diseases, eosinophil-related diseases and basophil-related diseases.

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GB007 INC3013 SCIENCE PARK ROAD SUITE 200 SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ly, Tai Wei San Diego, US 28 73
Potter, Garrett Thomas Redlands, US 14 41
Tran, Marie Chantal Siu-Ying Arcadia, US 4 7

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