Heterocyclic compounds for the inhibition of integrins and use thereof

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United States of America Patent

PATENT NO 8309735
APP PUB NO 20090203745A1
SERIAL NO

12300530

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to compounds of formula (I) wherein: A is a radical selected from the group comprising aromatic heterocyclic 5-membered ring systems; Ar is a radical selected from the group comprising optionally substituted 5- and 6-membered aromatic ring systems, whereby the ring system contains 0, 1, 2 or 3 heteroatoms selected from the group comprising N, O and S; Z is a linker and Ψ is a radical of formula (II) and their use for the inhibition of integrin.

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Patent Owner(s)

Patent OwnerAddress
TAKEDA PHARMACEUTICAL COMPANY LIMITED1-1 DOSHOMACHI 4-CHOME CHUO-KU OSAKA-SHI OSAKA

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Christner-Albrecht, Claudia Berlin, DE 2 23
Hummel, Gerd Berlin, DE 22 178
Kalkhof, Holger Berlin, DE 2 23
Osterkamp, Frank Berlin, DE 31 175
Reineke, Ulrich Berlin, DE 34 219
Scharn, Dirk Berlin, DE 20 96
Stragies, Roland Berlin, DE 11 94
Vossmeyer, Doerte Berlin, DE 2 23
Zahn, Grit Berlin, DE 4 73
Zischinsky, Gunther Berlin, DE 13 71

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