Method for induction of differentiation of ES cell
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United States of America Patent
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Nov 13, 2012
Grant Date -
Mar 8, 2012
app pub date -
May 30, 2008
filing date -
May 30, 2007
priority date (Note) -
Expired
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Abstract
It is an object of the present invention to establish a system for reliably differentiating an ES cell into a hepatic cell. The present invention provides a method for inducing the differentiation of an ES cell into a hepatic cell, which comprises, in the presence of an M15 cell, culturing a mammal-derived ES cell in the presence of activin and bFGF, and then culturing the ES cell in the presence of dexamethasone, HGF, and oncostatin M.
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