Intranasal compositions
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United States of America Patent
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Nov 13, 2012
Grant Date -
Sep 30, 2010
app pub date -
Nov 10, 2008
filing date -
Nov 9, 2007
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Abstract
A liquid aqueous formulation for the intranasal administration of apomorphine includes:
- (a) at least about 15 mg/ml of apomorphine; and(b) a solubilising agent selected from (i) at least one polyoxyethylene-polyoxypropylene copolymer (poloxamer);(ii) at least one cyclodextrin; and(iii) at least one cyclodextrin together with chitosan.The formulations of the invention can be used in the treatment or management of Parkinson's disease and erectile dysfunction.
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- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
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ARCHIMEDES DEVELOPMENT LIMITED | NOTTINGHAM NG7 2TN |
International Classification(s)
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
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Cheng, Yu-Hui | Nottingham, GB | 8 | 69 |
# of filed Patents : 8 Total Citations : 69 | |||
Watts, Peter | Nottingham, GB | 16 | 170 |
# of filed Patents : 16 Total Citations : 170 |
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- 13 Age
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Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
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Fee | Large entity fee | small entity fee | micro entity fee |
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Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
Full Text
US Patent No: 8309108
Intranasal compositions
Abstract
A liquid aqueous formulation for the intranasal administration of apomorphine includes:
- (a) at least about 15 mg/ml of apomorphine; and(b) a solubilising agent selected from (i) at least one polyoxyethylene-polyoxypropylene copolymer (poloxamer);(ii) at least one cyclodextrin; and(iii) at least one cyclodextrin together with chitosan.The formulations of the invention can be used in the treatment or management of Parkinson's disease and erectile dysfunction.
Description
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Legal Events
Date | Code | Event | Description |
---|---|---|---|
Dec 21, 2020 | LAPS | LAPSE FOR FAILURE TO PAY MAINTENANCE FEES | free format text: PATENT EXPIRED FOR FAILURE TO PAY MAINTENANCE FEES (ORIGINAL EVENT CODE: EXP.); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY |
Dec 21, 2020 | STCH | INFORMATION ON STATUS: PATENT DISCONTINUATION | free format text: PATENT EXPIRED DUE TO NONPAYMENT OF MAINTENANCE FEES UNDER 37 CFR 1.362 |
Nov 13, 2020 | FP | LAPSED DUE TO FAILURE TO PAY MAINTENANCE FEE | Effective Date: Nov 13, 2020 |
Jul 06, 2020 | FEPP | FEE PAYMENT PROCEDURE | free format text: MAINTENANCE FEE REMINDER MAILED (ORIGINAL EVENT CODE: REM.); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY |
Apr 26, 2016 | FPAY | FEE PAYMENT | year of fee payment: 4 |
Nov 13, 2012 | I | Issuance | |
Oct 24, 2012 | STCF | INFORMATION ON STATUS: PATENT GRANT | free format text: PATENTED CASE |
Sep 30, 2010 | P | Published | |
May 24, 2010 | AS | ASSIGNMENT | free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:WATTS, PETER;CHENG, YU-HUI;REEL/FRAME:024495/0512 Owner name: ARCHIMEDES DEVELOPMENT LIMITED, UNITED KINGDOM Effective Date: May 24, 2010 |
Nov 10, 2008 | F | Filing | |
Nov 09, 2007 | PD | Priority Date |

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