Aminoisoquinoline thrombin inhibitor with improved bioavailability

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United States of America Patent

PATENT NO 8299091
APP PUB NO 20100305153A1
SERIAL NO

12376529

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to the compound N-(2-oxo-2-propoxyethyl)-β-phenyl-D-phenyl-alanyl-N-[(1-amino-6-iso-quinolinyl)methyl]-L-prolinamide or a pharmaceutically acceptable salt thereof, to a pharmaceutical composition comprising said compound, as well as to the use of the compound for the manufacture of a medicament for treating or for preventing thrombin mediated diseases.

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Patent Owner(s)

Patent OwnerAddress
MERCK SHARP & DOHME B V2031 BN HAARLEM

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bennett, David Jonathan Newhouse, GB 30 125
Gilfillan, Robert Newhouse, GB 7 8

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