Activation of endothelial nitric oxide synthase by midkine and uses therefor in effecting vasodilation
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United States of America Patent
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Oct 16, 2012
Grant Date -
Aug 5, 2010
app pub date -
Mar 28, 2008
filing date -
Mar 30, 2007
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Abstract
The object is to find a nitric oxide synthase activator, a method for the administration of the activator, and the amount of the activator to be administered. Disclosed is a nitric oxide synthase activator comprising a midkine family protein or a midkine derivative as an active ingredient. Specifically disclosed is a nitric oxide synthase activator which is intended to be administered through the blood, a coronary artery or a vein and which comprises a midkine family protein or a midkine derivative as an active ingredient.
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