Transgenic mouse models of Aβ overexpression

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United States of America Patent

PATENT NO 8283517
APP PUB NO 20090098052A1
SERIAL NO

12209321

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Abstract

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A transgenic non-human animal, in particular a transgenic mouse encoding Aβ peptide proteins, which have been implicated in Aβ peptide-related diseases. Cells and cell lines comprising transgenes encoding for Aβ peptide. Methods and compositions for evaluating agents that affect Aβ peptide, for use in compositions for the treatment of Aβ peptide-related diseases.

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Patent Owner(s)

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PROBIODRUG AG06120 HALLE/SAALE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cynis, Holger Halle/Saale, DE 20 89
Demuth, Hans-Ulrich Halle/Saale, DE 116 1907
Graubner, Sigrid Munich, DE 10 16
Jagla, Wolfgang Windach, DE 2 9
Schilling, Stephan Halle/Saale, DE 51 597

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