Process for producing recombinant fibrinogen highly producing cell and highly producing cell

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United States of America Patent

PATENT NO 8283137
APP PUB NO 20100151522A1
SERIAL NO

10566266

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Abstract

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When genes encoding three kinds of proteins constituting fibrinogen, an α chain (or variant of α chain), a β chain and a γ chain (or variant of γ chain) are incorporated into an animal cell, a constitutional ratio of respective genes is such that a α chain (and/or variant of γ chain) gene is an equal amount to a 1000-fold amount relative to an α chain (and/or variant of α chain) gene and a β chain gene and, further, by using a baculovirus P35 gene, a recombinant fibrinogen highly producing cell is prepared.

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Patent Owner(s)

Patent OwnerAddress
KM BIOLOGICS CO LTD1-6-1 OKUBO KITA-KU KUMAMOTO-SHI KUMAMOTO 860-8568

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Maeda, Hiroaki Kikuchi, JP 98 1001
Matsuyama, Reiko Kikuchi, JP 4 4

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