Method to enhance hemodynamic stability using oxygen carrying compositions
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United States of America Patent
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Oct 2, 2012
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Nov 23, 2009
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Aug 31, 2004
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Abstract
The present invention relates to methods for enhancing the hemodynamic stability of an individual undergoing surgery by administering a composition comprising a hemoglobin-based oxygen carrier. In one embodiment, the present invention relates to the use of polyalkylene oxide modified hemoglobins with reduced cooperativity and a high oxygen affinity to enhance oxygen offloading as a preventative measure to avoid hemodynamic stability-related complications during surgery.
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