Methods and apparatus for centrifugal liquid chromatography
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United States of America Patent
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Oct 2, 2012
Grant Date -
Sep 16, 2010
app pub date -
Mar 12, 2010
filing date -
Mar 13, 2009
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Abstract
Apparatus and methods related to centrifugal liquid chromatography are described. An angular velocity can be simultaneously imparted to a large number of chromatographic enclosures. Via centrifugal forces, a mobile phase fluid including a sample can be driven through a stationary phase within the chromatographic enclosure to perform a chromatographic separation process on components of the sample. The use of centrifugation as a driving force can allow significantly smaller stationary phase particles to be employed as compared to high performance liquid chromatography (HPLC). Further, for an equivalent chromatographic separation process, the use of centrifugation can provide much greater separation efficiencies than HPLC.
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