Viral variants

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United States of America Patent

PATENT NO 8273527
APP PUB NO 20080171313A1
SERIAL NO

11905904

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B virus variants exhibiting complete or partial resistance to nucleoside analogues and/or reduced interactivity with antibodies to viral surface components including reduced sensitivity. The present invention further contemplates assays for detecting such viral variants which assays are useful in monitoring anti-viral therapeutic regimes and in developing new or modified vaccines directed against viral agents and in particular hepatitis B virus variants.

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Patent Owner(s)

Patent OwnerAddress
EVIVAR MEDICAL PTY LTDSUITE 501 100 VICTORIA PARADE EAST MELBOURNE VICTORIA 3002

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ayres, Anna West Brunswick, AU 19 72
Bartholomeusz, Angeline Carnegie, AU 7 7
Littlejohn, Margaret Coburg, AU 7 22
Locarnini, Stephen East St Kilda, AU 13 32

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