Contrast agents
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United States of America Patent
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Sep 25, 2012
Grant Date -
May 6, 2010
app pub date -
Dec 19, 2007
filing date -
Dec 20, 2006
priority date (Note) -
Expired
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Abstract
The present invention provides novel compounds and pharmaceutical compositions containing such compounds, wherein the compounds have affinity for proteoglycans. The compounds comprise an amino acid based core unit linked to positively charged moieties. The compounds further comprise at least one imaging moiety detectable in in vivo imaging making the compounds useful as diagnostic contrast agents for imaging of proteoglycans, such as heparan sulphate proteoglycans.
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