Use of dapsone as a neuroprotector in cerebral infarction
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United States of America Patent
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Sep 18, 2012
Grant Date -
Mar 11, 2010
app pub date -
Mar 16, 2004
filing date -
Jul 22, 2003
priority date (Note) -
Expired
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Abstract
The use of dapsone is the first effective treatment against the disabling consequences associated with cerebral infarction in patients. Dapsone was evaluated as a neuroprotector in the cerebral infarction model produced by the occlusion of the middle cerebral artery in rats and in patients suffering from acute cerebral infarction caused by thromboembolism. In both studies, dapsone displayed a reduction of between 70 and 90% in the adverse effects which occur as a consequence of the infarction.
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