Compositions and methods utilizing DNA polymerases
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United States of America Patent
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Sep 18, 2012
Grant Date -
Aug 21, 2003
app pub date -
Jun 29, 2001
filing date -
Oct 29, 1999
priority date (Note) -
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Abstract
The invention features a novel isolated Family B DNA polymerase, a Thermococcus polymerase JDF-3, and mutant recombinant forms thereof. Mutant polymerases of the invention are deficient in 3′ to 5′ exonuclease activity and/or exhibit reduced discrimination against non-conventional nucleotides relative to the wild-type form of the polymerase.
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