Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
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United States of America Patent
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Sep 11, 2012
Grant Date -
May 14, 2009
app pub date -
Jan 13, 2009
filing date -
Aug 31, 1998
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Abstract
This invention provides antibodies that specifically bind to and neutralize botulinum neurotoxin type A (BoNT/A) and the epitopes bound by those antibodies. The antibodies and derivatives thereof and/or other antibodies that specifically bind to the neutralizing epitopes provided herein can be used to neutralize botulinum neurotoxin and are therefore also useful in the treatment of botulism.
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