Label free kinase assays and reagents

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United States of America Patent

PATENT NO 8263377
APP PUB NO 20120157328A1
SERIAL NO

12061175

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This disclosure describes methods and compositions for measuring the binding specificity, kinetics and affinity of kinase inhibitors indirectly using mass sensing analytical techniques, such as SPR, through the competitive displacement of detectable signal-inducing kinase binding molecule. Further provided are methods for preparing such molecules.

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Patent Owner(s)

Patent OwnerAddress
SUZHOU PUXIN LIFE SCIENCE & TECHNOLOGY LTDSUITE 507 BUILDING B2 NANO BIOLOGICAL PARK XINGHU STREET NO 218 SUZHOU INDUSTRIAL PARK SUZHOU 215124

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cicirelli, Michael Kirkland, US 11 16
Dudek, Ronald P Sammamish, US 2 3
Parker, Timothy C Bothell, US 3 19

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