Preparation of biomolecules
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United States of America Patent
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Sep 11, 2012
Grant Date -
Nov 27, 2008
app pub date -
Dec 21, 2006
filing date -
Dec 22, 2005
priority date (Note) -
Expired
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Abstract
The present invention relates to a method of separating a target from a liquid, which includes providing a polymer in an aqueous liquid, which polymer comprises at least one hydrophobic portion; contacting the polymer-containing liquid with the liquid comprising the target; applying a stimulus to the resulting mixture; and maintaining it until a reversible phase separation is obtained. One phase is polymer-rich and contains target(s) and another phase is polymer-poor. By either maintaining the stimulus, or applying a different stimulus and maintaining it, the polymer-rich phase is transformed into a substantially solid phase.
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