Microorganism that displays biotin on cell surface

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United States of America Patent

PATENT NO 8252577
APP PUB NO 20090275110A1
SERIAL NO

12431102

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided is a microorganism that can display, on the cell surface, any molecules other than a molecule comprising amino acids, more specifically, a microorganism that displays biotin on a cell surface. The microorganism is capable of co-expressing a biotinylating enzyme and an acceptor peptide having a sequence recognized by the biotinylating enzyme, wherein the acceptor peptide is expressed on the cell surface, so that lysine of the acceptor peptide is biotinylated to display biotin on the cell surface. Also provided is a method for displaying an intended molecule, including not only a molecule comprising amino acids but also any molecules, on a cell surface of a microorganism.

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Patent Owner(s)

Patent OwnerAddress
KANSAI CHEMICAL ENGINEERING CO LTD9-7 MINAMINANAMATSUCHO 2-CHOME AMAGASAKI-SHI HYOGO 6600053 ?6600053
BIO-ENERGY CORPORATIONAMAGASAKI-SHI HYOGO 660-0053

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fukuda, Hideki Kobe, JP 102 1783
Kondo, Akihiko Kobe, JP 53 259
Noda, Hideo Amagasaki, JP 67 631
Tanaka, Tsutomu Kobe, JP 399 11273

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