High affinity, anti-human IgE antibodies
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United States of America Patent
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Aug 28, 2012
Grant Date -
Mar 17, 2011
app pub date -
Mar 27, 2009
filing date -
Feb 1, 2003
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Abstract
The invention relates to high affinity human monoclonal antibodies, particularly those directed against isotypic determinants of immunoglobulin E (IgE), as well as direct equivalents and derivatives of these antibodies. These antibodies bind to their respective target with an affinity at least 100 fold greater than the original parent antibody. These antibodies are useful for diagnostics, prophylaxis and treatment of disease.
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