Crystalline irinotecan hydrochloride and methods for its preparation
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United States of America Patent
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Aug 21, 2012
Grant Date -
Jul 15, 2010
app pub date -
Nov 10, 2009
filing date -
Nov 11, 2008
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Abstract
Disclosed is a crystalline form of irinotecan hydrochloride (I) and processes for the preparation thereof from crude irinotecan hydrochloride or another polymorphic form of irinotecan. Said crystalline form is particularly suitable for industrial use, because it is easily filtered and possesses characteristics of high stability and purity.
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