Methods and compositions for treating disorders caused by a deficiency in a gene product of a CLN gene

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United States of America Patent

PATENT NO 8242086
APP PUB NO 20100152123A1
SERIAL NO

12617318

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Abstract

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The present invention provides methods and compositions for treating a disorder associated with a deficiency in a gene product of a CLN gene in a subject (e.g., neuronal ceroid lipofuscinosis (NCL)), comprising administering to the subject an effective amount of a sphingolipid (e.g., galactosylceramide, ceramide, lysophosphatidic acid, sulfatide and any combination thereof), thereby treating the disorder in the subject.

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Patent Owner(s)

Patent OwnerAddress
DUKE UNIVERSITY2812 ERWIN ROAD SUITE 406 BOX 90083 DURHAM NC 27705
THE AMERICAN UNIVERSITY OF BEIRUTBLISS STREET P O BOX 11-0236 RIAD EL SOLH BEIRUT 1107-2020

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boustany, Rose-Mary N Beirut, LB 6 9

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