Mammalian expression vector with a highly efficient secretory signal sequence

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United States of America Patent

PATENT NO 8241870
APP PUB NO 20100240097A1
SERIAL NO

12601037

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Abstract

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The present invention relates to a mammalian cell based expression and secretion system and the expression and secretion of recombinant proteins by using secretory signal peptides. The present invention also relates to an expression cassette useful for the secretion of a heterologous gene from a mammalian cell, in particular a CHO cell. The present invention is also directed to a method of secreting a heterologous protein from mammalian cells such as CHO cells.

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Patent Owner(s)

Patent OwnerAddress
LONZA BIOLOGICS PLC228-230 BATH ROAD SLOUGH BERKSHIRE SL1 4DX

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Rance, James London, GB 5 47
Young, Robert London, GB 98 908

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