Method and apparatus for the filtration of biological samples
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United States of America Patent
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Jul 31, 2012
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app pub date -
Feb 15, 2009
filing date -
Dec 29, 2005
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Abstract
A separation module and method are disclosed for processing a liquid sample and providing high conversion by operating a single-pass tangential-flow process without a recirculation loop. In one embodiment, the separation module includes three reservoirs and has at least one long, thin channel with a large ratio of channel membrane area to: channel void volume; volume of a sample feed reservoir; and volume of the feed sample. In another embodiment, the separation module includes two reservoirs and a hydrophobic vent. The single-pass process provides high conversion while operating with relatively low pressure sources.
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