Adenine derivative as inhibitors of HSP90 for the treatment of cancer
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United States of America Patent
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Jul 10, 2012
Grant Date -
Feb 11, 2010
app pub date -
Nov 5, 2007
filing date -
Nov 6, 2006
priority date (Note) -
Expired
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Abstract
The invention provides a compound which is (a) an amino acid derivative of formula (I) or a tautomer thereof, or (b) a pharmaceutically acceptable salt, N-oxide, hydrate or solvate thereof: wherein R1, R2, L1, Het, A, x, y and W are as defined herein. The compounds are useful in the treatment of diseases mediated by HSP90.
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