Allorestricted peptide-specific T cells

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United States of America Patent

PATENT NO 8217009
SERIAL NO

12304918

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Abstract

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The present invention is directed to a T cell receptor (TCR) recognizing antigenic peptides derived from tumor-associated antigen FMNL1/KW13 and being capable of inducing peptide specific killing of a target cell. The present invention is further directed to one antigenic peptides derived from tumor-associated antigen FMNL1/KW13, to an antigen specific T cell, comprising said TCR, to a nucleic acid coding for said TCR and to the use of the antigen specific T cells for the manufacture of a medicament for the treatment of malignancies characterized by overexpression of FMNL1/KW13.

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Patent Owner(s)

Patent OwnerAddress
HELMHOLTZ ZENTRUM MUNCHEN DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT1 INGOLSTÄDTER LANDSTRASSE NEUHERBERG 85764

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Busch, Dirk Munich, DE 9 57
Krackhardt, Angela Munich, DE 4 36
Schuster, Ingrid Munich, DE 9 46

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