Process for preparing rosuvastatin calcium
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United States of America Patent
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Jul 3, 2012
Grant Date -
Feb 4, 2010
app pub date -
Dec 11, 2007
filing date -
Dec 13, 2006
priority date (Note) -
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Abstract
The present invention relates to an improved process for preparing (2E)-3-[4-(4-fluorophenyl)-6-iso-propyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal of Formula I which is an intermediate useful in the preparation of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoicacid]calcium salt of Formula II.
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