5-phenyl-isoxazole-3-carboxamide derivatives as TRPV1 modulators
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United States of America Patent
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Jul 3, 2012
Grant Date -
Mar 17, 2011
app pub date -
Jul 31, 2008
filing date -
Aug 2, 2007
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Expired
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Abstract
The present invention relates to isoxazole-3-carboxamide derivative having the general Formula (I), or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same, as well as to the use of said isoxazole-3-carboxamide derivatives for the treatment of TRPV1 mediated disorders, such as acute and chronic pain disorders, acute and chronic neuropathic pain, acute and chronic inflammatory pain, respiratory diseases, and lower urinary tract disorders.
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