Method for treating neurological and neuropathic diseases using rho kinase inhibitor compounds

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United States of America Patent

PATENT NO 8207195
APP PUB NO 20090325934A1
SERIAL NO

12492848

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention is directed to methods of preventing or treating neurological or neuropathic diseases or conditions associated with excessive inflammation, neurodegeneration, neuro-remodeling, and axonal/neurite retraction. Particularly, this invention relates to methods treating neurological or neuropathic diseases such as cerebral ischemia, stroke, neuropathic pain, spinal cord injury, Alzheimer's disease, and multiple sclerosis, using novel rho kinase inhibitor compounds. The method comprises identifying a subject in need of the treatment, and administering to the subject an effective amount of a novel rho kinase inhibitor compound to treat the disease.

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Patent Owner(s)

Patent OwnerAddress
INSPIRE PHARMACEUTICALS INC4222 EMPEROR BLVD SUITE 200 DURHAM NC 27703

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fulcher, Emilee H Cary, US 9 225
Lampe, John W Cary, US 27 363
Navratil, Tomas Carrboro, US 36 384
Peterson, Ward M Morrisville, US 32 563

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