Synthetic RNA-based agonists of TLR7

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United States of America Patent

PATENT NO 8202974
APP PUB NO 20100215642A1
SERIAL NO

12703612

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to the therapeutic use of stabilized oligoribonucleotides as immune modulatory agents for immune therapy applications. Specifically, the invention provides RNA-based oligoribonucleotides with improved nuclease and RNase stability and that selectively induce immune modulatory activity through TLR7.

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Patent Owner(s)

Patent OwnerAddress
IDERA PHARMACEUTICALS INC167 SIDNEY STREET CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Agrawal, Sudhir Shrewsbury, US 223 8509
Kandimalla, Ekambar Southboro, US 59 812
Lan, Tao Arlington, US 15 151
Wang, Daqing Bedford, US 91 766

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