Purification method of lactone compounds containing unsaturated alkyl group by extraction with silver ion solution
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United States of America Patent
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Jun 5, 2012
Grant Date -
Jul 14, 2011
app pub date -
Mar 18, 2011
filing date -
Sep 18, 2008
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Abstract
The present invention relates to a method for separating and purifying a lactone compound with an unsaturated alkyl group from a lactone compound with a saturated alkyl group which is an analog thereof. More specifically, the present invention relates to a method for effectively separating a lactone compound with an unsaturated alkyl group such as FK506 at high purity by extraction with a silver ion (Ag+) solution without use of column chromatography.
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