Process for producing di(pyrimidine nucleoside 5'-)polyphosphate
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United States of America Patent
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Jun 5, 2012
Grant Date -
Jan 21, 2010
app pub date -
Jul 25, 2007
filing date -
Jul 26, 2006
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Abstract
A di(pyrimidine nucleoside 5′-)polyphosphate is synthesized by converting a pyrimidine nucleoside 5′-triphosphate into a pyrimidine nucleoside 5′-cyclic triphosphate by use of a condensing agent, and subsequently reacting the pyrimidine nucleoside 5′-cyclic triphosphate with a pyrimidine nucleotide in the presence of a salt of a metal selected from among magnesium, manganese, and iron.
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