Composition for diagnosing amyloid-related diseases
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United States of America Patent
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Jun 5, 2012
Grant Date -
Jun 5, 2008
app pub date -
Nov 25, 2005
filing date -
Nov 26, 2004
priority date (Note) -
Expired
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Abstract
A composition for diagnosing amyloid-related diseases, which comprises a flavone derivative, a chalcone derivative, a styrylchromone derivative, or a coumarin derivative, is provided. These compounds have high binding specificity to an amyloid β protein, high permeability to a blood-brain barrier, and ability to rapidly disappear from sites other than cerebral senile plaque. Accordingly, the composition of the present invention using these compounds enables the diagnosis of amyloid-related diseases with high precision.
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