Talarazole metabolites
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United States of America Patent
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May 29, 2012
Grant Date -
Nov 18, 2010
app pub date -
Oct 17, 2007
filing date -
Oct 17, 2006
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Abstract
Novel metabolites of talarazole of formula (I) have been isolated and characterized, wherein R═H, OH, OSO3H or O-gly; R1, ═H, OH, OSO3H, O-gly or =0; and gly=a glucuronate, or a pharmaceutically acceptable salt thereof. These compounds are targeted for the treatment of various skin-, hair- and nail-associated disorders.
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